Nasal Tumor Vaccination Protects against Lung Tumor Development by Induction of Resident Effector and Memory Anti-Tumor Immune Responses

• 主要な著者: Michael Donkor (著者), Jamie Choe (著者), Danielle Marie Reid (著者), Byron Quinn (著者), Mark Pulse (著者), Amalendu Ranjan (著者), Pankaj Chaudhary (著者), Harlan P. Jones (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Lung metastasis is a leading cause of cancer-related deaths. Here, we show that intranasal delivery of our engineered CpG-coated tumor antigen (Tag)-encapsulated nanoparticles (NPs)-nasal nano-vaccine-significantly reduced lung colonization by intravenous challenge of an extra-pulmonary tumor. Prote...