Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma

• Main Authors: Stephanie Denk (Author), Rebecca Wiegner (Author), Felix M. Hönes (Author), David A. C. Messerer (Author), Peter Radermacher (Author), Manfred Weiss (Author), Miriam Kalbitz (Author), Christian Ehrnthaller (Author), Sonja Braumüller (Author), Oscar McCook (Author), Florian Gebhard (Author), Sebastian Weckbach (Author), Markus Huber-Lang (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe tissue trauma-induced systemic inflammation is often accompanied by evident or occult blood-organ barrier dysfunctions, frequently leading to multiple organ dysfunction. However, it is unknown whether specific barrier molecules are shed into the circulation early after trauma as potential ind...