Regulation of protein abundance in genetically diverse mouse populations

• Main Authors: Gregory R. Keele (Author), Tian Zhang (Author), Duy T. Pham (Author), Matthew Vincent (Author), Timothy A. Bell (Author), Pablo Hock (Author), Ginger D. Shaw (Author), Joao A. Paulo (Author), Steven C. Munger (Author), Fernando Pardo-Manuel de Villena (Author), Martin T. Ferris (Author), Steven P. Gygi (Author), Gary A. Churchill (Author)
• Format: Book
• Published: Elsevier, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Genetically diverse mouse populations are powerful tools for characterizing the regulation of the proteome and its relationship to whole-organism phenotypes. We used mass spectrometry to profile and quantify the abundance of 6,798 proteins in liver tissue from mice of both sexes across 58 C...