Physiologically‐based pharmacokinetic modeling to predict drug interactions of lemborexant with CYP3A inhibitors
Abstract Lemborexant, a recently approved dual orexin receptor antagonist for treatment of adults with insomnia, is eliminated primarily by cytochrome P450 (CYP)3A metabolism. The recommended dose of lemborexant is 5 mg once per night, with a maximum recommended dose of 10 mg once daily. A physiolog...
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| Main Authors: | , , , , |
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| Format: | Book |
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Wiley,
2021-05-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |