Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice

P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are co-localized at the blood-brain barrier, where they display functional redundancy to restrict the brain distribution of dual P-gp/BCRP substrate drugs. We used positron emission tomography (PET) with the metabolically stable P-gp/...

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Váldodahkkit: Irene Hernández-Lozano (Dahkki), Severin Mairinger (Dahkki), Alexander Traxl (Dahkki), Michael Sauberer (Dahkki), Thomas Filip (Dahkki), Johann Stanek (Dahkki), Claudia Kuntner (Dahkki), Thomas Wanek (Dahkki), Oliver Langer (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: MDPI AG, 2021-08-01T00:00:00Z.
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3rd Floor Main Library

oažžasuvvan: 3rd Floor Main Library
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