Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

• Główni autorzy: Jittima Tomacha (Autor), Hasaya Dokduang (Autor), Sureerat Padthaisong (Autor), Nisana Namwat (Autor), Poramate Klanrit (Autor), Jutarop Phetcharaburanin (Autor), Arporn Wangwiwatsin (Autor), Tueanjit Khampitak (Autor), Supinda Koonmee (Autor), Attapol Titapun (Autor), Apiwat Jarearnrat (Autor), Narong Khuntikeo (Autor), Watcharin Loilome (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been reported in many cancers. Therefore, elucidati...