Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been reported in many cancers. Therefore, elucidati...

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Main Authors: Jittima Tomacha (Author), Hasaya Dokduang (Author), Sureerat Padthaisong (Author), Nisana Namwat (Author), Poramate Klanrit (Author), Jutarop Phetcharaburanin (Author), Arporn Wangwiwatsin (Author), Tueanjit Khampitak (Author), Supinda Koonmee (Author), Attapol Titapun (Author), Apiwat Jarearnrat (Author), Narong Khuntikeo (Author), Watcharin Loilome (Author)
Format: Book
Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
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3rd Floor Main Library

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