The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding

• मुख्य लेखकों: Renee A. Rotolo (लेखक), Vladimir Dragacevic (लेखक), Predrag Kalaba (लेखक), Ernst Urban (लेखक), Martin Zehl (लेखक), Alexander Roller (लेखक), Judith Wackerlig (लेखक), Thierry Langer (लेखक), Marco Pistis (लेखक), Maria Antonietta De Luca (लेखक), Francesca Caria (लेखक), Rebecca Schwartz (लेखक), Rose E. Presby (लेखक), Jen-Hau Yang (लेखक), Shanna Samels (लेखक), Merce Correa (लेखक), Gert Lubec (लेखक), John D. Salamone (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Animal studies of effort-based choice behavior are being used to model effort-related motivational dysfunctions in humans. With these procedures, animals are offered a choice between high-effort instrumental actions leading to highly valued reinforcers vs. low effort/low reward options. Several prev...