Exploring the relationship of hyaluronic acid molecular weight and active targeting efficiency for designing hyaluronic acid-modified nanoparticles

• Main Authors: Lu Zhong (Author), Yanying Liu (Author), Lu Xu (Author), Qingsong Li (Author), Dongyang Zhao (Author), Zhenbao Li (Author), Huicong Zhang (Author), Haotian Zhang (Author), Qiming Kan (Author), Jin Sun (Author), Zhonggui He (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although it is reported that the targeting ability of hyaluronic acid (HA)-based nanoparticles (NPs) is molecular weight (MW) dependent, the influence of HA MW on targeting efficiency of HA-functionalized NPs and the underlying mechanism remain elusive. In this study, we constituted three HA-functio...