Semi-Synthetic Dihydrotestosterone Derivatives Modulate Inherent Multidrug Resistance and Sensitize Colon Cancer Cells to Chemotherapy

Semi-Synthetic Dihydrotestosterone Derivatives Modulate Inherent Multidrug Resistance and Sensitize Colon Cancer Cells to Chemotherapy

Multidrug resistance (MDR) is a serious hurdle to successful cancer therapy. Here, we examined the efficiency of novel semi-synthetic dihydrotestosterone derivatives, more specifically androstano-arylpyrimidines in inhibiting the efflux activity of ATP-binding cassette (ABC) transporters and sensiti...

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Main Authors: Ferenc István Nagy (Author), Dóra Izabella Adamecz (Author), Ádám Baji (Author), Ágnes Kiricsi (Author), Ildikó Huliák (Author), Andrea Rónavári (Author), Zoltán Kónya (Author), Éva Frank (Author), Mohana Krishna Gopisetty (Author), Mónika Kiricsi (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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