The Production of Antibiotics Must Be Reoriented: Repositioning Old Narrow-Spectrum Antibiotics, Developing New Microbiome-Sparing Antibiotics

• Main Authors: Sylvain Diamantis (Author), Nicolas Retur (Author), Benjamin Bertrand (Author), Florence Lieutier-Colas (Author), Philippe Carenco (Author), Véronique Mondain (Author), on behalf of PROMISE Professional Community Network on Antimicrobial Resistance (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of broad-spectrum antibiotics to control multidrug-resistant bacteria is an outdated business model. This strategy has led to the introduction of highly effective antibiotics, but their widespread use has contributed to the emergence of even broader antibiotic resistance. In a strate...