Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET Imaging

Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET Imaging

Positron emission tomography (PET) imaging of P-glycoprotein (P-gp) in the blood-brain barrier can be important in neurological diseases where P-gp is affected, such as Alzheimer´s disease. Radiotracers used in the imaging studies are present at very small, nanomolar, concentration, whereas in vitro...

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Main Authors: Renske M. Raaphorst (Author), Heli Savolainen (Author), Mariangela Cantore (Author), Evita van de Steeg (Author), Aren van Waarde (Author), Nicola A. Colabufo (Author), Philip H. Elsinga (Author), Adriaan A. Lammertsma (Author), Albert D. Windhorst (Author), Gert Luurtsema (Author)
Format: Book
Published: MDPI AG, 2017-09-01T00:00:00Z.
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