Osteoclasts Are Required for Hematopoietic Stem and Progenitor Cell Mobilization but Not for Stress Erythropoiesis in Plasmodium chabaudi adami Murine Malaria

• Egile Nagusiak: Hugo Roméro (Egilea), Christopher Warburton (Egilea), Jaime Sanchez-Dardon (Egilea), Tatiana Scorza (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2016-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The anemia and inflammation concurrent with blood stage malaria trigger stress haematopoiesis and erythropoiesis. The activity of osteoclasts seems required for the mobilization of hematopoietic stem and progenitor cells (HSPC) from the bone marrow to the periphery. Knowing that BALB/c mice with acu...