Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates

• Main Authors: Alessio Nocentini (Author), Daniela Vullo (Author), Sonia Del Prete (Author), Sameh M. Osman (Author), Fatmah A.S. Alasmary (Author), Zeid AlOthman (Author), Clemente Capasso (Author), Fabrizio Carta (Author), Paola Gratteri (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of monothiocarbamates (MTCs) was investigated for the inhibition of the β-class carbonic anhydrase (CAs, EC 4.2.1.1) from the fungal parasite Malassezia globosa, MgCA. These MTCs incorporate various scaffolds, among which aliphatic amine with 1-4 carbons atom in their molecule, morpholine,...