Phorbol Ester Modulation of Ca2+ Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones

• मुख्य लेखकों: Gary J. Stephens (लेखक), Li Yang (लेखक), Iqbal Topia (लेखक), Toni Schneider (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2013-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Phorbol esters are analogues of diacylglycerol which activate C1 domain proteins, such as protein kinase C (PKC). Phorbol ester/PKC pathways have been proposed as potential therapeutic targets for chronic pain states, potentially by phosphorylating proteins involved in nociception, such as voltage-d...