Synthesis, Evaluation of Cytotoxicity and Molecular Docking Studies of the 7-Acetamido Substituted 2-Aryl-5-bromo-3-trifluoroacetylindoles as Potential Inhibitors of Tubulin Polymerization

The 3-trifluoroacetyl–substituted 7-acetamido-2-aryl-5-bromoindoles 5a–h were prepared and evaluated for potential antigrowth effect in vitro against human lung cancer (A549) and cervical cancer (HeLa) cells and for the potential to inhibit tubulin polymerization. The correspondi...

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Main Authors: Malose J. Mphahlele (Author), Nishal Parbhoo (Author)
Format: Book
Published: MDPI AG, 2018-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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