PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages of Sepsis

• Үндсэн зохиолчид: Juan Du (Зохиогч), Guoli Li (Зохиогч), Mingxi Hua (Зохиогч), Junyan Han (Зохиогч), Yu Hao (Зохиогч), Hui Zeng (Зохиогч), Ang Li (Зохиогч), Yaxian Kong (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Hindawi Limited, 2020-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The cecal ligation and perforation (CLP) model is the gold standard for the polymicrobial sepsis. In the CLP mice, the myeloid cells play an important role in septic shock. The phenotypes and the activation state of the macrophage and neutrophil correlate with their metabolism. In the present study,...