Neutrophil Extracellular DNA Traps Induce Autoantigen Production by Airway Epithelial Cells

• Main Authors: Youngwoo Choi (Author), Le Duy Pham (Author), Dong-Hyun Lee (Author), Ga-Young Ban (Author), Ji-Ho Lee (Author), Seung-Hyun Kim (Author), Hae-Sim Park (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The hypothesis of autoimmune involvement in asthma has received much recent interest. Autoantibodies, such as anti-cytokeratin (CK) 18, anti-CK19, and anti-α-enolase antibodies, react with self-antigens and are found at high levels in the sera of patients with severe asthma (SA). However, the mechan...