Synthesis, antileishmanial activity and QSAR studies of 2-chloro- N -arylacetamides

ABSTRACT We describe herein the synthesis and evaluation of the antileishmanial activity against promastigote forms of Leishmania amazonensis and cytotoxicity to murine macrophages of a series of 2-chloro-N-arylacetamide derivatives. All compounds were active, except one (compound 3). Compound 5 pre...

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Main Authors: Stefânia Neiva Lavorato (Author), Mariana Costa Duarte (Author), Pedro Henrique Rocha De Andrade (Author), Eduardo Antonio Ferraz Coelho (Author), Ricardo José Alves (Author)
Format: Book
Published: Universidade de São Paulo, 2017-04-01T00:00:00Z.
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