Enhanced cytotoxic potential of Orthosiphon stamineus extract in MCF-7 cells through suppression of nucleolin and bcl2

• Main Authors: Renuka Saravanan (Author), Brindha Pemaiah (Author), Sriram Sridharan (Author), Mahesh Narayanan (Author), Sivakumar Ramalingam (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present study was to analyze the anti-cancer effect of Orthosiphon stamineus leaf extract on MCF-7 cells. Ethyl acetate extract of the plant was eluted and pooled into 6 fractions based on their Rf values and the fractions were tested for cytotoxicity. Fraction 3 was found effective (...