Ikaros-Associated Diseases: From Mice to Humans and Back Again

• Main Authors: Brigette Boast (Author), Cristiane de Jesus Nunes-Santos (Author), Hye Sun Kuehn (Author), Sergio D. Rosenzweig (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The normal expression of Ikaros (IKZF1) is important for the proper functioning of both the human and murine immune systems. Whilst our understanding of IKZF1 in the immune system has been greatly enhanced by the study of mice carrying mutations in Ikzf1, analyses of human patients carrying germline...