Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole.

• Main Authors: Claudia Magalhães Calvet (Author), Tatiana Araújo Silva (Author), Diane Thomas (Author), Brian Suzuki (Author), Ken Hirata (Author), Jair Lage Siqueira-Neto (Author), James H McKerrow (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas' Disease, caused by the protozoan parasite Trypanosoma cruzi, is responsible for up to 41% of the heart failures in endemic areas in South America and is an emerging infection in regions of North America, Europe, and Asia. Treatment is suboptimal due to two factors. First, the lack of an...