Method of detection of dexamethasone in biological tissues and its application to assess the local kinetics of this drug Authors

• Main Authors: Dina V. Yunina (Author), Valentin P. Ageev (Author), Andrey V. Zaborovskiy (Author), Larisa A. Tararina (Author), Sergei V. Tsaregorodtsev (Author), Alexander V. Kokorev (Author), Dmitry N. Andreev (Author), Aleksandra E. Pyanzina (Author), Vasilisa I. Shlyapkina (Author), Nikolay A. Pyataev (Author), Oleg A. Kulikov (Author)
• Format: Book
• Published: Belgorod National Research University, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The study of the pharmacokinetics of glucocorticosteroids is often required to solve fundamental and applied tasks of pharmacology. HPLC methods based on ultraviolet detection are attractive due to their availability, but their sensitivity is low enough to study in vivo kinetics. In th...