A Brief History of IL-1 and IL-1 Ra in Rheumatology

• Autors principals: Jean-Michel Dayer (Autor), Francesca Oliviero (Autor), Leonardo Punzi (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The history of what, in 1979, was called interleukin-1 (IL-1), orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP) (1974) and then in rheumatology on the role in tissue destruction in rheumatoid...