The regulatory roles of Smad2/3 protein and SMURF2 gene expression in granulosa cells of germinal vesicle and metaphase II oocytes in polycystic ovarian syndrome: A case-control study

• Main Authors: Marzieh Ghorbani (Author), Marzieh Sanoee Farimani (Author), Iraj Khodadadi (Author), Sina Mohagheghi (Author), Iraj Amiri (Author), Heidar Tayebinia (Author)
• Format: Book
• Published: Shahid Sadoughi University of Medical Sciences, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background: The impaired functions of granulosa cells (GCs) in the delayed development and immaturity of oocytes have been reported in polycystic ovary syndrome (PCOs). Even with ovarian stimulation, a large number of oocytes in these patients are still in the stage germinal vesicle (GV). O...