Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation

• Main Authors: Zin Zin Ei (Author), Pilaiwanwadee Hutamekalin (Author), Peerada Prommeenate (Author), Avtar Singh (Author), Soottawat Benjakul (Author), Kittichate Visuttijai (Author), Pithi Chanvorachote (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Endoplasmic reticulum (ER) stress contributes to endothelium pathological conditions. Chitooligosaccharides (COS) have health benefits, but their effect on endothelial cells is unknown. We demonstrate for the first time a protective effect of COS against ER-induced endothelial cell damage.Ob...