Functional characterization of peroxiredoxins from the human protozoan parasite Giardia intestinalis.

• Main Authors: Daniela Mastronicola (Author), Micol Falabella (Author), Fabrizio Testa (Author), Leopoldo Paolo Pucillo (Author), Miguel Teixeira (Author), Paolo Sarti (Author), Lígia M Saraiva (Author), Alessandro Giuffrè (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The microaerophilic protozoan parasite Giardia intestinalis, causative of one of the most common human intestinal diseases worldwide, infects the mucosa of the proximal small intestine, where it has to cope with O2 and nitric oxide (NO). Elucidating the antioxidant defense system of this pathogen la...