PTEN Expression Regulates Gap Junction Connectivity in the Retina

• Main Authors: Ashley M. Chen (Author), Shaghauyegh S. Azar (Author), Alexander Harris (Author), Nicholas C. Brecha (Author), Luis Pérez de Sevilla Müller (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Manipulation of the phosphatase and tensin homolog (PTEN) pathway has been suggested as a therapeutic approach to treat or prevent vision loss due to retinal disease. In this study, we investigated the effects of deleting one copy of Pten in a well-characterized class of retinal ganglion cells calle...