Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging.

• Main Authors: Dennis J Grab (Author), Olga V Nikolskaia (Author), Bertrand Courtioux (Author), Oriel M M Thekisoe (Author), Stefan Magez (Author), Maxim Bogorad (Author), J Stephen Dumler (Author), Sylvie Bisser (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Objective</h4>Where human African trypanosomiasis (HAT) patients are seen, failure to microscopically diagnose infections by Trypanosoma brucei gambiense in blood smears and/or cerebrospinal fluid (CSF) in the critical early stages of the disease is the single most important factor i...