Apolipoprotein A-I Mimetic Peptide L-4F Suppresses Granulocytic-Myeloid-Derived Suppressor Cells in Mouse Pancreatic Cancer

• Main Authors: Meiyu Peng (Author), Qi Zhang (Author), Yanqing Liu (Author), Xiangdong Guo (Author), Jiyu Ju (Author), Lingzhi Xu (Author), Yuanyuan Gao (Author), Daquan Chen (Author), Dongzhen Mu (Author), Rongxin Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

L-4F is an apolipoprotein A-I (ApoA-I) mimetic peptide, it was engineered to imitate the anti-inflammatory and anti-oxidative activity of ApoA-I. In this paper, H7 cell was used to construct a mouse model of pancreatic cancer in situ, and the mice were treated with L-4F. Then, the development of pan...