Using a Machine Learning Approach to Identify Low-Frequency and Rare FLG Alleles Associated with Remission of Atopic Dermatitis

Atopic dermatitis (AD) is a common relapsing inflammatory skin disease. FLG is the gene most consistently associated with AD. Loss-of-function variants in FLG have been previously associated with AD. Low-frequency and rare alleles (minor allele frequency < 5%) in this gene have been given less at...

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Main Authors: Ronald Berna (Author), Nandita Mitra (Author), Ole Hoffstad (Author), Bradley Wubbenhorst (Author), Katherine L. Nathanson (Author), David J. Margolis (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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