Investigation of the Effects of the Short QT Syndrome D172N Kir2.1 Mutation on Ventricular Action Potential Profile Using Dynamic Clamp

• Asıl Yazarlar: Chunyun Du (Yazar), Randall L. Rasmusson (Yazar), Glenna C. Bett (Yazar), Brandon Franks (Yazar), Henggui Zhang (Yazar), Jules C. Hancox (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The congenital short QT syndrome (SQTS) is a cardiac condition that leads to abbreviated ventricular repolarization and an increased susceptibility to arrhythmia and sudden death. The SQT3 form of the syndrome is due to mutations to the KCNJ2 gene that encodes Kir2.1, a critical component of channel...