Fak silencing impairs osteogenic differentiation of bone mesenchymal stem cells induced by uniaxial mechanical stretch

• Autori principali: Pei Hu (Autore), Xiaowen Zhu (Autore), Chuang Zhao (Autore), Jing Hu (Autore), En Luo (Autore), Bin Ye (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2019-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background/purpose: Mechanical stretch plays a key role in promoting proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs) in distraction osteogenesis (DO). A better understanding of how the extracellular biomechanical stimulation is transferred to intracellular signal expr...