An aptamer interacting with heat shock protein 70 shows therapeutic effects and prognostic ability in serous ovarian cancer

• Main Authors: Chang-Ni Lin (Author), Yi-Cheng Tsai (Author), Ching-Cheng Hsu (Author), Yu-Ling Liang (Author), Yi-Ying Wu (Author), Chieh-Yi Kang (Author), Chun-Hong Lin (Author), Pang-Hung Hsu (Author), Gwo-Bin Lee (Author), Keng-Fu Hsu (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ovarian cancer (OvCa) is the most lethal gynecologic malignancy owing to its high chemoresistance and late diagnosis, which lead to a poor prognosis. Hence, developing new therapeutic modalities is important for OvCa patient treatment. Our previous results indicated that a novel aptamer, Tx-01, can...