Anti-Interleukin-16-Neutralizing Antibody Attenuates Cardiac Inflammation and Protects against Cardiac Injury in Doxorubicin-Treated Mice

• Main Authors: Jianwei Zhang (Author), Zicong Yang (Author), Zhishan Liang (Author), Mengjie Wang (Author), Changxing Hu (Author), Chao Chang (Author), Lei Shi (Author), Qingwei Ji (Author), Ling Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Interleukin-16 (IL-16) is an important inflammatory regulator and has been shown to have a powerful effect on the regulation of the inflammatory response. Cardiac inflammation has been reported to be closely related to doxorubicin- (DOX-) induced cardiac injury. In this study, the role o...