Melatonin Successfully Rescues the Hippocampal Molecular Machinery and Enhances Anti-oxidative Activity Following Early-Life Sleep Deprivation Injury

• Main Authors: Hung-Ming Chang (Author), Hsing-Chun Lin (Author), Hsin-Lin Cheng (Author), Chih-Kai Liao (Author), To-Jung Tseng (Author), Ting-Yi Renn (Author), Chyn-Tair Lan (Author), Li-You Chen (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Early-life sleep deprivation (ESD) is a serious condition with severe cognitive sequelae. Considering hippocampus plays an essential role in cognitive regulation, the present study aims to determine whether melatonin, a neuroendocrine beard with significant anti-oxidative activity, would greatly dep...