Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP-mTOR Axis

Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP-mTOR Axis

Recent studies undoubtedly show that the mammalian target of rapamycin (mTOR) and the Hippo-Yes-associated protein 1 (YAP) pathways are important mediators of mechanical cues. The crosstalk between these pathways as well as de-regulation of their signaling has been implicated in multiple tumor types...

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Main Authors: Adam Frtús (Author), Barbora Smolková (Author), Mariia Uzhytchak (Author), Mariia Lunova (Author), Milan Jirsa (Author), Martin Hof (Author), Piotr Jurkiewicz (Author), Vladimir I. Lozinsky (Author), Lucie Wolfová (Author), Yuriy Petrenko (Author), Šárka Kubinová (Author), Alexandr Dejneka (Author), Oleg Lunov (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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