Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer

• Main Authors: Jiangang Zhao (Author), Jiahui Li (Author), Hans A. Schlößer (Author), Felix Popp (Author), Marie Christine Popp (Author), Hakan Alakus (Author), Karl-Walter Jauch (Author), Christiane J. Bruns (Author), Yue Zhao (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer stem cells (CSCs) have been identified as a subpopulation of stem-like cancer cells with the ability of self-renewal and differentiation in hematological malignancies and solid tumors. Pancreatic cancer is one of the most lethal cancers worldwide. CSCs are thought to be responsible for cancer...