Identification of Potential Multitarget Compounds against Alzheimer's Disease through Pharmacophore-Based Virtual Screening

• المؤلفون الرئيسيون: Géssica Oliveira Mendes (مؤلف), Moysés Fagundes de Araújo Neto (مؤلف), Deyse Brito Barbosa (مؤلف), Mayra Ramos do Bomfim (مؤلف), Lorena Silva Matos Andrade (مؤلف), Paulo Batista de Carvalho (مؤلف), Tiago Alves de Oliveira (مؤلف), Daniel Luciano Falkoski (مؤلف), Eduardo Habib Bechelane Maia (مؤلف), Marcelo Siqueira Valle (مؤلف), Laila Cristina Moreira Damázio (مؤلف), Alisson Marques da Silva (مؤلف), Alex Gutterres Taranto (مؤلف), Franco Henrique Andrade Leite (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive loss of cognitive functions, and it is the most prevalent type of dementia worldwide, accounting for 60 to 70% of cases. The pathogenesis of AD seems to involve three main factors: deficiency in cholinergic tra...