Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA

• Main Authors: Francesco Lechi (Author), Jonas Eriksson (Author), Luke R. Odell (Author), Olivia Wegrzyniak (Author), John Löfblom (Author), Fredrik Y. Frejd (Author), Bo Zhang (Author), Olof Eriksson (Author)
• Format: Book
• Published: SpringerOpen, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background In recent years, the interest in Al[18F]F as a labeling agent for Positron Emission Tomography (PET) radiotracers has risen, as it allows for fast and efficient fluorine-18 labeling by harnessing chelation chemistry. The introduction of Restrained Complexing Agent (RESCA) as a ch...