Integrated virtual screening and in vitro studies for exploring the mechanism of triterpenoids in Chebulae Fructus alleviating mesaconitine-induced cardiotoxicity via TRPV1 channel

• Main Authors: Liangliang Song (Author), Shuo Mi (Author), Ying Zhao (Author), Ziqin Liu (Author), Jing Wang (Author), Hongyue Wang (Author), Wenhui Li (Author), Jiasheng Wang (Author), Wenting Zu (Author), Hong Du (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In traditional Mongolian or Tibetan medicine in China, Chebulae Fructus (CF) is widely used to process or combine with aconitums to decrease the severe toxicity of aconitums. Researches in this area have predominantly focused on tannins, with few research on other major CF components for...