In silico analysis of six known Leishmania major antigens and in vitro evaluation of specific epitopes eliciting HLA-A2 restricted CD8 T cell response.
BACKGROUND: As a potent CD8(+) T cell activator, peptide vaccine has found its way in vaccine development against intracellular infections and cancer, but not against leishmaniasis. The first step toward a peptide vaccine is epitope mapping of different proteins according to the most frequent HLA ty...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2011-09-01T00:00:00Z.
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