Preparation and characterization of cefuroxime axetil solid dispersions using poloxamer 188

• Κύριοι συγγραφείς: Thaeer Sankari (Συγγραφέας), Sahar Al-Hariri (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Universidade de São Paulo, 2019-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The main objective of the present work was to enhance the solubility and dissolution rate of poorly water-soluble drug cefuroxime axetil (CA) by formulating it into solid dispersions (SDs) with water soluble carrier poloxamer 188. Different methods were employed to prepare the dispersion, such as: S...