A Novel De Novo Missense Mutation in HNF4A Resulting in Sulfonylurea-Responsive Maturity-onset Diabetes of the Young

• Main Authors: Sezer Acar (Author), Ayhan Abacı (Author), Korcan Demir (Author), Taha Reşid Özdemir (Author), Berk Özyılmaz (Author), Ece Böber (Author)
• Format: Bog
• Udgivet: Galenos Yayinevi, 2018-09-01T00:00:00Z.
• Fag: article
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Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes, with autosomal-dominant inheritance, which usually develops before 25 years of age. MODY is classically caused by a heterozygous mutation of genes known to affect insulin production or secretion. Heterozygous inactivating h...