Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli

• Main Authors: Jacquelyn Blake-Hedges (Author), Dan Groff (Author), Wilson Foo (Author), Jeffrey Hanson (Author), Elenor Castillo (Author), Miao Wen (Author), Diana Cheung (Author), Mary Rose Masikat (Author), Jian Lu (Author), Young Park (Author), Nina Abi Carlos (Author), Hans Usman (Author), Kevin Fong (Author), Abigail Yu (Author), Sihong Zhou (Author), Joyce Kwong (Author), Cuong Tran (Author), Xiaofan Li (Author), Dawei Yuan (Author), Trevor Hallam (Author), Gang Yin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTTherapeutic bioconjugates are emerging as an essential tool to combat human disease. Site-specific conjugation technologies are widely recognized as the optimal approach for producing homogeneous drug products. Non-natural amino acid (nnAA) incorporation allows the introduction of bioconjuga...