LINC00473‐modified bone marrow mesenchymal stem cells incorporated thermosensitive PLGA hydrogel transplantation for steroid‐induced osteonecrosis of femoral head: A detailed mechanistic study and validity evaluation

• Main Authors: Yingxing Xu (Author), Yaping Jiang (Author), Yingzhen Wang (Author), Bin Jia (Author), Song Gao (Author), Haiyang Yu (Author), Haining Zhang (Author), Chengyu Lv (Author), Haiyan Li (Author), Tao Li (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The pathogenesis of steroid‐induced osteonecrosis of the femoral head (SONFH) involves a glucocorticoid‐induced imbalance of osteogenic and adipogenic differentiation, and apoptosis of bone marrow mesenchymal stem cells (BMSCs). An increasing number of genes, especially noncoding RNAs, have...