A female of progressive familial intrahepatic cholestasis type 3 caused by heterozygous mutations of ABCB4 gene and her cirrhosis improved after treatment of ursodeoxycholic acid: a case report

• Hauptverfasser: Fei Qiao (Verfasst von), Feng Ren (Verfasst von), Weiting Lu (Verfasst von), Haoran Yang (Verfasst von), Guiling Mo (Verfasst von), Shuangshuang Wang (Verfasst von), Lina Liu (Verfasst von), Xiangtao Xu (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2023-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Progressive familial intrahepatic cholestasis (PFIC) is a group of rapidly progressive autosomal recessive disorders characterized by intrahepatic cholestasis. PFIC-3 is caused by mutations in the ATP-binding cassette subfamily B member 4 gene (ABCB4), which encodes multidrug res...