Regulation mechanism of endoplasmic reticulum stress on metabolic enzymes in liver diseases

• Main Authors: Shaojun Zhou (Author), Kaiwen Cheng (Author), Yi Peng (Author), Yuxi Liu (Author), Qingqing Hu (Author), Su Zeng (Author), Xuchen Qi (Author), Lushan Yu (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The endoplasmic reticulum (ER) plays a pivotal role in protein folding and secretion, Ca2+ storage, and lipid synthesis in eukaryotic cells. When the burden of protein synthesis and folding required to be handled exceeds the processing capacity of the ER, the accumulation of misfolded/unfolded prote...