Inhibitors of sodium-glucose cotransporter 2: risk of ketoacidosis

• Main Authors: T. M. Bukatina (Author), A. S. Kazakov (Author), N. Yu. Velts (Author), M. A. Darmostukova (Author), E. Yu. Kolesnikova (Author), R. N. Alyautdin (Author), B. K. Romanov (Author)
• Format: Book
• Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SGLT2 inhibitors form a new class of hypoglycemic drugs. Despite of the pharmacodynamic profile, at the moment the opinion about their safety is controversial. This is due to increased number of reports given by FDA and EMA on the risk of serious adverse reactions - ketoacidosis, which is not specif...