Dynamics of parasite clearance in cutaneous leishmaniasis patients treated with miltefosine.

• Main Authors: Thomas P C Dorlo (Author), Pieter P A M van Thiel (Author), Gerard J Schoone (Author), Ymkje Stienstra (Author), Michèle van Vugt (Author), Jos H Beijnen (Author), Peter J de Vries (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parasite loads were quantified in repeated skin biopsies from lesions of 2 patients with Old-World cutaneous leishmaniasis (CL) caused by Leishmania major and L. infantum during and after treatment with miltefosine. Miltefosine induced a rapid therapeutic effect on both infections with an initial de...