Carbazole Derivatives Binding to Bcl-2 Promoter Sequence G-quadruplex

• Principais autores: Agata Głuszyńska (Autor), Joanna Kosman (Autor), Shang Shiuan Chuah (Autor), Marcin Hoffmann (Autor), Shozeb Haider (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In this study, we used ultraviolet-visible (UV-Vis), fluorescence, and circular dichroism (CD) techniques, as well as molecular modeling, to probe the interactions between carbazole derivatives and the G-quadruplex structure formed in the promoter region of gene <i>Bcl-2</i>. This gene i...