Carbazole Derivatives Binding to Bcl-2 Promoter Sequence G-quadruplex

• Main Authors: Agata Głuszyńska (Author), Joanna Kosman (Author), Shang Shiuan Chuah (Author), Marcin Hoffmann (Author), Shozeb Haider (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we used ultraviolet-visible (UV-Vis), fluorescence, and circular dichroism (CD) techniques, as well as molecular modeling, to probe the interactions between carbazole derivatives and the G-quadruplex structure formed in the promoter region of gene <i>Bcl-2</i>. This gene i...